Spyre Therapeutics (SYRE) Stock

NASDAQ

$80.10

+1.87% Close Oct 15

SYRE stock daily candlestick chart with 50, 150 and 200-day moving averagesOpen interactive chart
One year of daily prices through Oct 15, 2026. The interactive chart has the full history.

SYRE stock price today

Last close
$80.10
Day range
$76.87 to $80.88
52-week range
$21.01 to $110.18
From 52-week high
−27.3%
Average volume (50 days)
1.3M
1 week
+0.3%
1 month
−12.1%
3 months
−20.1%
Year to date
+144.5%
1 year
+281.4%
3 years
+517.1%
5 years
−59.0%

Is SYRE stock in an uptrend?

Yes, SYRE stock is in an uptrend: it does not meet the Minervini Trend Template criteria and 1 of the 2 Daily Pivot Breakout momentum filters is active. Price is above its 200-day moving average.

Daily Pivot momentum filters
1 of 2 active
100-day ROC
+8.2% filter at 40%: off
100-day EMA slope
+62.7% filter at 25%: active
Trend state
Uptrend
Minervini Trend Template
Not met on the latest scan
50-day average
Below
150-day average
Below
200-day average
Above
200-day slope (1 month)
+8.76%
ATR (14) % of price
7.12%

Momentum filters from the Daily Pivot Breakout indicator: 100-day rate of change and 100-day EMA slope, each against its minimum.

SYRE support and resistance levels

LevelPriceFrom close
Daily Pivot resistance (pivot high)$95.27+18.9%
50-day SMA$92.78+15.8%
21-day EMA$85.68+7.0%
30-week SMA$83.05+3.7%
Latest Daily Pivot low$82.93+3.5%
9-day EMA$82.65+3.2%
150-day SMA$81.21+1.4%
200-day SMA$69.85−12.8%

Levels above the close act as resistance, levels below as support. Last close $80.10.

SYRE breakout and scanner signals

ScannerLast signal (free view, 5 sessions late)Past year
Daily Pivot BreakoutSep 17, 20268
Minervini Trend TemplateAug 25, 202626
Episodic PivotNone in the last year0
Ichimoku TK crossSep 1, 2026 (bearish)New signal in the last 5 sessions. See it in the journal.1
9/21 EMA crossAug 27, 2026 (bearish)1

SYRE seasonality by month

  1. Jan+3.5%40% up
  2. Feb+2.9%50% up
  3. Mar+2.2%50% up
  4. Apr−1.0%20% up
  5. May−5.5%45% up
  6. Jun+12.7%45% up
  7. Jul+0.8%45% up
  8. Aug+9.1%73% up
  9. Sep+1.5%55% up
  10. Oct+10.9%40% up
  11. Nov+0.5%40% up
  12. Dec−1.9%40% up

Average monthly return over 10+ years of stored daily closes, and the share of years each month closed higher.

SYRE bull and bear case

What looks strong

  • 1 of 2 Daily Pivot momentum filters is active (100-day ROC 8.2%, 100-day EMA slope 62.7%).
  • The 50, 150 and 200-day averages are stacked in uptrend order.
  • Price is above a rising 200-day moving average.
  • Had a Daily Pivot Breakout on 2026-09-17.

What looks weak

  • Does not meet the Minervini Trend Template on the latest scan.
  • Price is below the 50-day moving average.
  • Price closed below its latest Daily Pivot low.

Drawn only from the data on this page. Not a recommendation.

SYRE news and SEC filings, last 30 days

No SEC filings in the last 30 days.

SYRE valuation and fundamentals

Gross margin
–
Operating margin
–
Profit margin
–
Return on equity
–
Revenue growth (quarter, y/y)
–

Who owns SYRE?

Held by insiders
–
Held by institutions
–
Short interest (% of shares)
–

What does Spyre Therapeutics, Inc. do?

Updated Oct 15, 2026. Prices and fundamentals: Source: Twelve Data. Filings and insider trades: SEC EDGAR. Charts: TradingView Lightweight Charts. Educational information, not investment advice.